【 English Name 】 Potassium t-Butoxide

Molecular formula: C4H9KO

【 Molecular Weight 】 112.23

CA login number [865-47-4]

【 Structural Formula 】 t-BuOK

【 Physical Properties 】 It appears as a white, easily hygroscopic powder; Its melting point range is 256258 degrees Celsius (decomposition); At 2526 degrees Celsius, the solubility of different solvents varies, for example, 0.27 g/100 g solvent in hexane, 2.27 g/100 g solvent in acetone, 4.34 g/100 g solvent in ether, 17.80 g/100 g solvent in tert butanol, and up to 25.00 g/100 g solvent in THF.

[Preparation and Commodity] Commercial reagents available on the market; Before use, it is usually recommended to refine by sublimation purification, with purification conditions of 220 degrees Celsius/1 millimeter of mercury or 180 degrees Celsius/0.5 millimeter of mercury. It can prepare tert butanol solution by reacting potassium with anhydrous tert butanol under nitrogen protection.

【 Precautions 】 Caution should be exercised during operation to avoid direct contact with eyes, skin, and clothing; Due to its ability to react with water, oxygen, and carbon dioxide, exposure to air at high temperatures may trigger combustion. To ensure safety, it is recommended to operate in an inert gas environment and divide into small portions for sealed storage under nitrogen protection.

T-BuOK is a commonly used base in the field of organic synthesis, with a stronger alkalinity than alkali metal hydroxides and primary and secondary alkoxides, but weaker than amino alkali metals and their alkyl derivatives. The reason why it is widely used in organic synthesis is not only because it is affordable and easy to obtain, but also because its alkalinity can be flexibly adjusted according to the different reaction solvents selected.